---
title: 'Funding Daily Summary: What Happened on October 22, 2026'
headline: AptaDir raises €40 million seed round for fragile X program
description: Arctic Therapeutics also raised $21.5 million to advance two autoimmune
  candidates toward clinical testing.
url: https://thebench.bio/news/funding/2026-10-22
topic: funding
date: '2026-10-22'
covers:
- '2026-10-22'
date_published: '2026-10-22T12:01:04Z'
date_modified: '2026-10-22T12:01:04Z'
tags:
- Funding
- Industry
sources: 2
publisher: TheBench.Bio
---

# Funding Daily Summary: What Happened on October 22, 2026

**AptaDir raises €40 million seed round for fragile X program**

Arctic Therapeutics also raised $21.5 million to advance two autoimmune candidates toward clinical testing.

## Today in brief

AptaDir Therapeutics raised €40 million to advance its fragile X syndrome program, which aims to reactivate silenced genes. [1] Arctic Therapeutics raised $21.5 million to advance two autoimmune drug candidates toward clinical testing. [2]

## Also worth knowing

- AptaDir is developing RNA-DNA chimeras that block a methylation enzyme at a specific genetic location to reactivate silenced genes. CEO Giovanni Amabile said the financing should fund four years of work, including a Phase I trial he hopes to start in about 18 months. [1]
- Arctic said its round was oversubscribed and will support AT-002 and AT-003 as they move toward clinical testing. [2]

## The day in numbers

- **€40 million**: AptaDir's seed financing for its fragile X syndrome program. [1]
- **$21.5 million**: Arctic Therapeutics' financing to advance two autoimmune candidates. [2]

## Sources

1. [AptaDir: Switching silenced genes back on with targeted demethylation](<https://www.biocentury.com/article/661223/aptadir-switching-silenced-genes-back-on-with-targeted-demethylation?utm_source=bc_rss&utm_medium=rss>), BioCentury, 2026-10-22
2. [Arctic Therapeutics raises $21.5M to take autoimmune programs to clinic](<https://european-biotechnology.com/latest-news/arctic-therapeutics-raises-21-5m-to-take-autoimmune-programs-to-clinic/>), European Biotechnology, 2026-10-22

---

TheBench.Bio wrote this from the reporting cited above, with a language model drafting and editing.

[1]: <https://www.biocentury.com/article/661223/aptadir-switching-silenced-genes-back-on-with-targeted-demethylation?utm_source=bc_rss&utm_medium=rss>
[2]: <https://european-biotechnology.com/latest-news/arctic-therapeutics-raises-21-5m-to-take-autoimmune-programs-to-clinic/>
