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Funding Daily Summary

Funding Daily Summary: What Happened on October 4, 2026

Ai3Bio raises $48 million for immune-reset therapies

The startup’s first approach targets inflammatory T cells, with initial human tests possible next year.

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Today in brief

Ai3Bio emerged from stealth with a $48 million Series A to advance its immune-reset therapy pipeline.1 Its first intended target is Th17 cells, and initial human tests could begin next year.1

Also worth knowing

  • Ai3Bio’s antibody-guided lipid nanoparticles are designed to carry mRNA into target cells and activate the cGAS-STING pathway. Co-founder Jonathan Kagan said animal studies depleted inflammatory T cells, including in monkeys’ spleens and lymph nodes, but durability has not been demonstrated in people.1