An ecosystem for the biotech and life science industry, worldwide. It starts with the news below.
Industry
Researchers found that SLC25A34, a little-studied protein in the mitochondria of fat cells, acts as a switch that connects the body clock, temperature, and diet to how fat cells store and spend energy. The post Mitochondrial Transporter Connects Body Clock and Diet to Fat Burning…
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Industry
In the final installment of this series, Riaan and his family face the unknown after five years of developing a genetic medicine for Cockayne syndrome. The post Riaan’s Therapeutic Odyssey – Chapter 5: The Family appeared first on Inside Precision Medicine.
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Regulatory
Following an FDA meeting, Wave Life Sciences plans a single 2-year registrational trial of WVE-006, its GalNAc-conjugated RNA editing oligonucleotide for alpha-1 antitrypsin deficiency, with a 1-year interim analysis that could support accelerated approval based on biomarkers.
Regulatory
Regeneron and Sanofi expand their antibody alliance with four new drug candidates, FDA approves Camzyos for adolescents with obstructive hypertrophic cardiomyopathy, and Michael Abrams questions digital health's savings claims to employers.
Software
Intrinsically disordered proteins have resisted structure-based drug discovery because they lack a stable fold to model. Talus Bio's structure-free AI model sidesteps that limitation, targeting these proteins in their native environment instead of in isolation or from a predicted…
GEN
Industry
The frequently used biologic drug mepolizumab may cause an exaggerated inflammatory response in children with severe asthma who carry an incredibly common genetic variant when they contract a viral illness due to a gene–drug interaction. The post Asthma Biologic Interacts with Co…
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