Layoffs at Takeda
- Layoff events
- 9
- verified and sourced
- Roles reported
- At least 5,931
- events with no figure are not in this number
- Announced between
- Apr 2023 to Mar 2026
- Reported by
- Takeda / U.S. Securities and Exchange Commission, Takeda / Massachusetts Executive Office of Labor and Workforce Development, Reuters, Takeda / Massachusetts, Fierce Pharma, Massachusetts Executive Office of Labor and Workforce Development, The Boston Globe, and Fierce Biotech
This page records what we could verify and source. It is not a complete record of every job cut at Takeda: a layoff nobody published and nobody sent us is a layoff that is not on this page.
| Company | What happened | Roles reported | Share of staff | Where | Announced | Sources |
|---|---|---|---|---|---|---|
| Takeda |
Restructuring
Takeda launched the next phase of a global transformation program that the company later quantified as approximately 4,500 job reductions during fiscal 2026. |
4,500 | Not known | Company-wide | ||
| Takeda |
Takeda disclosed the elimination of 243 U.S. field positions as it reorganized its neuroscience commercial organization ahead of the approaching loss of exclusivity for Trintellix. |
243 | Not known | U.S. field employees assigned to 500 Kendall Street, Cambridge, United States | ||
| Takeda |
Restructuring
Takeda filed a Massachusetts WARN notice for up to 137 Massachusetts positions as it discontinued its cell-therapy efforts, with separations beginning in January 2026. |
137 | Not known | 650 Kendall St + 40 Landsdowne St + 300 Massachusetts Ave, Cambridge, United States | ||
| Takeda |
Restructuring
Takeda disclosed another Massachusetts workforce action affecting 79 positions across Cambridge and Lexington, with the final employment-loss count dependent on redeployment opportunities. |
Not known | Not known | Cambridge and Lexington, Massachusetts, United States |
1 source for Takeda |
|
| Takeda |
Restructuring
Takeda disclosed another Massachusetts workforce reduction affecting 220 employees across Cambridge and Lexington. |
220 | Not known | Cambridge and Lexington, Massachusetts, United States |
1 source for Takeda |
|
| Takeda |
Restructuring
Takeda disclosed 641 planned layoffs across two Massachusetts sites: 495 at its Cambridge headquarters and 146 at its Lexington campus. |
641 | Not known | Cambridge and Lexington, Massachusetts, United States |
1 source for Takeda |
|
| Takeda |
Site closure
Takeda announced plans to close its San Diego research site, where about 340 employees worked, while encouraging some staff to apply for roles at other Takeda locations. |
Not known | Not known | San Diego research site, San Diego, United States |
1 source for Takeda |
|
| Takeda |
Site closure
Takeda announced shutdown of production and R&D operations at an Austrian AAV gene-therapy site, affecting 190 employees. |
190 | Not known | AAV gene-therapy manufacturing and R&D site, Austria |
1 source for Takeda |
|
| Takeda |
Restructuring
Takeda announced workforce changes tied to its move away from early-stage AAV gene-therapy and rare-hematology research in Massachusetts. |
Not known | Not known | Massachusetts R&D sites, United States |
1 source for Takeda |
Where this comes from
Every cut listed for Takeda was entered by a person who checked it against a filing or a named report. Nothing is scraped and nothing publishes itself. What is not here is what we have not verified, not what did not happen.
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